Catalogue / GHRP-6
GHRP-6
A hexapeptide secretagogue carrying two tryptophan residues, which makes it the most oxidation-prone compound in routine circulation.
| Molecular formula | C46H56N12O6 |
| Average mass | 873.01 Da |
| Monoisotopic mass | 872.4446 Da |
| Written as | His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 |
| Class | Growth hormone secretagogues |
| Determination | Peptide analysis, catalogue compound |
| Price | 341 USD |
Computed at build time from the composition shown on this page, not transcribed from a supplier datasheet.
GHRP-6 has an average molecular weight of 873.01 daltons and a monoisotopic mass of 872.4446 daltons. Identity is confirmed by matching the measured deconvoluted mass to that figure, and purity is reported separately by reversed-phase chromatography at 214 nm. The two numbers answer different questions and neither substitutes for the other.
| Written sequence | His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 |
| Molecular formula | C46H56N12O6 |
This compound contains residues outside the standard twenty, so a theoretical mass cannot be derived from a one-letter sequence. The masses above are computed from the molecular formula instead.
This is not a technicality. A laboratory that computes an expected mass from a sequence lookup will get the wrong number for this compound, and will then either report a false mismatch or adjust the expectation to fit the measurement.
| Charge | m/z |
|---|---|
| [M+1H]+ | 873.452 |
| [M+2H]2+ | 437.23 |
These are the ions an electrospray source is expected to produce for a neutral mass of 872.4446 daltons, computed from the monoisotopic mass and the proton mass. They are what a raw spectrum should show before deconvolution.
A report that gives only a deconvoluted mass without the charge states it was derived from cannot be checked. Deconvolution is a calculation, and a calculation whose inputs are not shown is an assertion.
| Two tryptophans mean two independent oxidation sites. Mono-oxidised and di-oxidised species sit 16 and 32 daltons above the parent and are commonly present in aged material. |
| The peptide is light sensitive in solution. A sample that sat in a clear vial on a bench will report lower purity than the same material stored properly, and that is a real result about that vial. |
| Strong ultraviolet absorbance from the indole rings inflates the apparent area of tryptophan-containing impurities relative to non-aromatic ones. |
Every compound fails in its own way. A generic peptide method applied without regard to these specifics produces a number that looks like a result and is not one.
Short synthetic peptides, most carrying D-amino acids or unnatural residues that make them resistant to serum peptidases and invisible to sequence-only reasoning.
LC-MS identity against a certified reference standard, purity by RP-HPLC at 214 nm. D-isomers are not resolved by a conventional C18 column and are not claimed to be.
Where the delivered milligram figure matters rather than the percentage, net peptide content by combustion analysis and water by Karl Fischer are added, and the certificate carries a closed mass balance instead of a single purity number.
| LC-MS identity | Measured mass |
| RP-HPLC purity | Area at 214 nm |
| Net peptide content | Milligrams |
| Water content | Karl Fischer |
| Counter-ion | Ion chromatography |
| Bacterial endotoxins | USP <85> |
What is the molecular weight of GHRP-6?
The average molecular weight is 873.01 daltons and the monoisotopic mass is 872.4446 daltons, computed from the molecular formula C46H56N12O6 shown on this page. Both figures are calculated rather than transcribed, so they can be checked against the stated composition.
How is GHRP-6 tested for purity and identity?
LC-MS identity against a certified reference standard, purity by RP-HPLC at 214 nm. D-isomers are not resolved by a conventional C18 column and are not claimed to be. Purity describes the chromatographable fraction only and is not the same quantity as the peptide mass delivered per vial.
What goes wrong when GHRP-6 is analysed?
Two tryptophans mean two independent oxidation sites. Mono-oxidised and di-oxidised species sit 16 and 32 daltons above the parent and are commonly present in aged material.
What does GHRP-6 analysis cost at ANALYTON?
Peptide analysis, catalogue compound is priced at 341 US dollars, covering the determinations described on this page. Content, safety and elemental determinations are ordered alongside and are priced separately on the price list.
Other compounds in this class
Updated 2026-09-01. Masses computed at build, not transcribed.