Catalogue / MGF
MGF
Also written as Mechano growth factor, IGF-1Ec.
A splice variant of IGF-1 carrying a distinct C-terminal extension, supplied either as the full sequence or as the E-domain peptide alone.
| Class | Recombinant proteins |
| Determination | Peptide analysis, specialist compound |
| Price | 590 USD |
MGF is identified against a certified reference standard rather than against a published mass, because commercially supplied material varies in composition between suppliers. Purity is reported separately by reversed-phase chromatography at 214 nm and describes the chromatographable fraction only.
| Material sold as MGF is sometimes the full splice variant and sometimes only the 24 residue E-domain peptide. The two differ by several kilodaltons and are not interchangeable. |
| PEGylated grades are also sold under the same name, and the conjugate mass varies with the polymer used, so a single expected mass does not exist across suppliers. |
| No mass figure is published on this page because the composition supplied under this name is not consistent. Identity is established against a certified reference standard at the time of analysis. |
Every compound fails in its own way. A generic peptide method applied without regard to these specifics produces a number that looks like a result and is not one.
Expressed rather than synthesised. The failure modes are different: aggregation, deamidation, oxidation and truncation, none of which a single purity number captures.
RP-HPLC purity, size exclusion chromatography for dimer and higher aggregate, and where required a charge-variant separation. Aggregate is reported as a separate figure because a dimer is chemically still the same protein.
Where the delivered milligram figure matters rather than the percentage, net peptide content by combustion analysis and water by Karl Fischer are added, and the certificate carries a closed mass balance instead of a single purity number.
| LC-MS identity | Measured mass |
| RP-HPLC purity | Area at 214 nm |
| Net peptide content | Milligrams |
| Water content | Karl Fischer |
| Counter-ion | Ion chromatography |
| Bacterial endotoxins | USP <85> |
What is the molecular weight of MGF?
No molecular weight is published for MGF on this page, because the composition of commercially supplied material varies between suppliers and an unverified figure on an analytical site is worse than an absent one. Identity is established against a certified reference standard at the time of analysis.
How is MGF tested for purity and identity?
RP-HPLC purity, size exclusion chromatography for dimer and higher aggregate, and where required a charge-variant separation. Aggregate is reported as a separate figure because a dimer is chemically still the same protein. Purity describes the chromatographable fraction only and is not the same quantity as the peptide mass delivered per vial.
What goes wrong when MGF is analysed?
Material sold as MGF is sometimes the full splice variant and sometimes only the 24 residue E-domain peptide. The two differ by several kilodaltons and are not interchangeable.
What does MGF analysis cost at ANALYTON?
Peptide analysis, specialist compound is priced at 590 US dollars, covering the determinations described on this page. Content, safety and elemental determinations are ordered alongside and are priced separately on the price list.
Other compounds in this class
Updated 2026-09-01. Masses computed at build, not transcribed.