Catalogue / Elamipretide
Elamipretide
Also written as SS-31, MTP-131, Bendavia.
A tetrapeptide with an alternating cationic and aromatic motif, containing D-arginine and 2,6-dimethyltyrosine, neither of which is a standard residue.
| Molecular formula | C32H49N9O5 |
| Average mass | 639.79 Da |
| Monoisotopic mass | 639.3857 Da |
| Written as | D-Arg-Dmt-Lys-Phe-NH2 |
| Class | Signalling and mitochondrial peptides |
| Determination | Peptide analysis, specialist compound |
| Price | 590 USD |
Computed at build time from the composition shown on this page, not transcribed from a supplier datasheet.
Elamipretide has an average molecular weight of 639.79 daltons and a monoisotopic mass of 639.3857 daltons. Identity is confirmed by matching the measured deconvoluted mass to that figure, and purity is reported separately by reversed-phase chromatography at 214 nm. The two numbers answer different questions and neither substitutes for the other.
| Written sequence | D-Arg-Dmt-Lys-Phe-NH2 |
| Molecular formula | C32H49N9O5 |
This compound contains residues outside the standard twenty, so a theoretical mass cannot be derived from a one-letter sequence. The masses above are computed from the molecular formula instead.
This is not a technicality. A laboratory that computes an expected mass from a sequence lookup will get the wrong number for this compound, and will then either report a false mismatch or adjust the expectation to fit the measurement.
| Charge | m/z |
|---|---|
| [M+1H]+ | 640.393 |
| [M+2H]2+ | 320.7 |
These are the ions an electrospray source is expected to produce for a neutral mass of 639.3857 daltons, computed from the monoisotopic mass and the proton mass. They are what a raw spectrum should show before deconvolution.
A report that gives only a deconvoluted mass without the charge states it was derived from cannot be checked. Deconvolution is a calculation, and a calculation whose inputs are not shown is an assertion.
| Two of the four residues are non-proteinogenic. Theoretical mass has to come from the formula, not from a sequence lookup. |
| The dimethyltyrosine is fourteen daltons per methyl above tyrosine. A synthesis that used plain tyrosine is 28 daltons light and otherwise looks correct. |
| D-arginine is not resolved from L-arginine by achiral chromatography. |
Every compound fails in its own way. A generic peptide method applied without regard to these specifics produces a number that looks like a result and is not one.
Endogenous peptides with defined sequences, mostly unmodified, where the analytical question is simply whether the delivered material is the stated sequence at the stated mass.
LC-MS identity with deconvolution and RP-HPLC purity at 214 nm.
Where the delivered milligram figure matters rather than the percentage, net peptide content by combustion analysis and water by Karl Fischer are added, and the certificate carries a closed mass balance instead of a single purity number.
| LC-MS identity | Measured mass |
| RP-HPLC purity | Area at 214 nm |
| Net peptide content | Milligrams |
| Water content | Karl Fischer |
| Counter-ion | Ion chromatography |
| Bacterial endotoxins | USP <85> |
What is the molecular weight of Elamipretide?
The average molecular weight is 639.79 daltons and the monoisotopic mass is 639.3857 daltons, computed from the molecular formula C32H49N9O5 shown on this page. Both figures are calculated rather than transcribed, so they can be checked against the stated composition.
How is Elamipretide tested for purity and identity?
LC-MS identity with deconvolution and RP-HPLC purity at 214 nm. Purity describes the chromatographable fraction only and is not the same quantity as the peptide mass delivered per vial.
What goes wrong when Elamipretide is analysed?
Two of the four residues are non-proteinogenic. Theoretical mass has to come from the formula, not from a sequence lookup.
What does Elamipretide analysis cost at ANALYTON?
Peptide analysis, specialist compound is priced at 590 US dollars, covering the determinations described on this page. Content, safety and elemental determinations are ordered alongside and are priced separately on the price list.
Other compounds in this class
Updated 2026-09-01. Masses computed at build, not transcribed.