Catalogue / Cagrilintide

Cagrilintide

Also written as Amylin analogue.

A long-acting amylin analogue, usually submitted either alone or co-formulated with a GLP-1 analogue, which makes it a two-component quantitation rather than one.

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Computed constants
ClassIncretin analogues
DeterminationBlind identification, GLP-1 class
Price 468 USD

Cagrilintide is identified against a certified reference standard rather than against a published mass, because commercially supplied material varies in composition between suppliers. Purity is reported separately by reversed-phase chromatography at 214 nm and describes the chromatographable fraction only.

03What goes wrong with this compound
Co-formulated products need each component quantified separately against its own reference standard. A single combined assay figure is not a result for either component.
The molecule carries a disulfide bridge. Reduction during sample preparation opens the ring and shifts the mass by two daltons, so the preparation has to be non-reducing and stated as such.
No mass figure is published on this page because the formula has not been verified against a certified reference standard in house. Identity is established against the standard at the time of analysis.

Every compound fails in its own way. A generic peptide method applied without regard to these specifics produces a number that looks like a result and is not one.

Long-acting GLP-1 and dual agonists carrying a fatty acid chain on a lysine side chain. The class is chemically crowded, and analogues differ by a single substitution or a linker length.

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04How it is determined

LC-MS on the multiply charged envelope with deconvolution to the neutral mass, because analogues in this class co-elute closely and a retention-time match cannot separate them. Purity by RP-HPLC at 214 nm with a shallow acetonitrile gradient.

Where the delivered milligram figure matters rather than the percentage, net peptide content by combustion analysis and water by Karl Fischer are added, and the certificate carries a closed mass balance instead of a single purity number.

Determinations available
LC-MS identity Measured mass
RP-HPLC purity Area at 214 nm
Net peptide content Milligrams
Water content Karl Fischer
Counter-ion Ion chromatography
Bacterial endotoxins USP <85>
FAQCagrilintide

What is the molecular weight of Cagrilintide?

No molecular weight is published for Cagrilintide on this page, because the composition of commercially supplied material varies between suppliers and an unverified figure on an analytical site is worse than an absent one. Identity is established against a certified reference standard at the time of analysis.

How is Cagrilintide tested for purity and identity?

LC-MS on the multiply charged envelope with deconvolution to the neutral mass, because analogues in this class co-elute closely and a retention-time match cannot separate them. Purity by RP-HPLC at 214 nm with a shallow acetonitrile gradient. Purity describes the chromatographable fraction only and is not the same quantity as the peptide mass delivered per vial.

What goes wrong when Cagrilintide is analysed?

Co-formulated products need each component quantified separately against its own reference standard. A single combined assay figure is not a result for either component.

What does Cagrilintide analysis cost at ANALYTON?

Blind identification, GLP-1 class is priced at 468 US dollars, covering the determinations described on this page. Content, safety and elemental determinations are ordered alongside and are priced separately on the price list.

Other compounds in this class

Updated 2026-09-01. Masses computed at build, not transcribed.